Sunday 21 July 2013

New class of white blood cells discovered; potential target for better vaccine design

Article adapted by Medical News Today from original press release. Click 'references' tab above for source.
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The research findings described in this media release can be found in the 23 May issue of Immunity under the title, "IRF4 transcription factor-dependent CD11b+ dendritic cells in human and mouse control mucosal IL-17 cytokine responses" by Andreas Schlitzer1*, Naomi McGovern2*, Pearline Teo1, Teresa Zelante1, Koji Atarashi3, Donovan Low1, Adrian W.S. Ho1, Peter See1, Amanda Shin1, Pavandip Singh Wasan1, Guillaume Hoeffel1, Benoit Malleret1, Alexander Heiseke4, Samantha Chew1, Laura Jardine2, Harriet A. Purvis2, Catharien M.U. Hilkens2, John Tam5,6, Michael Poidinger1, E. Richard Stanley7, Anne B. Krug4, Laurent Renia1, Baalasubramanian Sivasankar8, Lai Guan Ng1, Matthew Collin2, Paola Ricciardi-Castagnoli1, Kenya Honda3, Muzlifah Haniffa2 and Florent Ginhoux1

Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), 138648, Singapore. Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne NE2 4HH, UK. Department of Immunology, Graduate School of Medicine, University of Tokyo, Tokyo 113-0033, Japan. II Medical Department, Klinikum Rechts der Isar, Technical University Munich, Ismaninger Str. 22, 81675 Munich, Germany. National University Hospital, 119074, Singapore. Yong Loo Lin School of Medicine, National University of Singapore, 119077, Singapore. Department of Developmental and Molecular Biology, Albert Einstein College of Medicine, Bronx, NY 10461, USA. Singapore Institute for Clinical Sciences, Agency for Science, Technology and Research (A*STAR), Singapore.

*These authors contributed equally to this work

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Agency for Science, Technology and Research (A*STAR), Singapore

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